So after recently coming back to skyrim after a long break I get the Hialgoboost update but now whenever I try to launch Skyrim SKSE I got this popup and the game doesn't launch. I'd appreciate it if I anybody could offer some help, cheers. 


I guess, you are using universal BOOST v5.0 and not legacy BOOST v.2.3c. (BTW, you should not mix the two!).

Uninstall BOOST and install it again. When you run it first time, you will get suggestion to update to the latest version. First time, do not update and make sure BOOST is working OK. 

Next time, do update and see whether the problem shows up. If yes, please let us know.